Thursday, May 26, 2011

Diffuse Injector For Therapeutic And Dye Delivery



Unlike an open hypodermic needle, fluid may be delivered to a volume of tissue surrounding the injector tip in many tiny increments, rather than a single large, mechanically traumatic bolus. For example, a 2-mm cylindrical active area on a 33-gauge diffuse injector typically provides 800 perforations of 10-um diameter on 25-um centers. An injected total volume of 1 ml delivers 1.25 ul from each perforations, reducing the likelihood of fluidic damage to surrounding tissue while delivered the fluid infiltrate. In research applications, typical syringe pumps are capable of 10^6: 1 dynamic range of volumetric delivery flow rate. This device allows a researcher to utilize more of that dynamic range without compromising adjacent tissue.