Developing a Hybrid Neuroprosthesis for Epilepsy Treatment

Developing A Hybrid Neuroprosthesis For Epilepsy Treatment: A Status Report

By Nandor Ludvig, M.D.


Check out this article from 2004 on the following link below. The author collaborated with Lenox Laser in the research and development.

http://faces.med.nyu.edu/research/research-articles/neuroprosthesis

Industrial Applications

Industrial process instrumentation and control applications include metered multi-orifice oriented or omni-directional high-pressure spray delivery of liquids and gases into a process fluid flow. In-line chemical reactant control and post-combustion pollution control are reasonable uses for this device. Multiple inlet ports provide a means for flow-controlled pre-mixing of injected fluid, and allow the controlled internal mixing of gas and liquid prior to external delivery.

The Lenox Laser Diffuse Injector

The Lenox Laser diffuse injector is a fluidic device consisting of a tube with a sealed tip embedded with a geometric array of multiple uniform laser-drilled perforations of controlled dimension. Liquid and /or gas is supplied by a pump or syringe under pressure to the open ports at the supply end of the tube, and is then forced out through the perforations to the surrounding environment.

Diffuse Injector For Therapeutic And Dye Delivery

Unlike an open hypodermic needle, fluid may be delivered to a volume of tissue surrounding the injector tip in many tiny increments, rather than a single large, mechanically traumatic bolus. For example, a 2-mm cylindrical active area on a 33-gauge diffuse injector typically provides 800 perforations of 10-um diameter on 25-um centers. An injected total volume of 1 ml delivers 1.25 ul from each perforations, reducing the likelihood of fluidic damage to surrounding tissue while delivered the fluid infiltrate. In research applications, typical syringe pumps are capable of 10^6: 1 dynamic range of volumetric delivery flow rate. This device allows a researcher to utilize more of that dynamic range without compromising adjacent tissue.